.

Publications

Selected Sampling of over 300

Abdollahi, T., Robertson, N.M., Abdollahi, A. and Litwack, G., Inhibition of TRAIL-induced apoptosis by IL-8 is mediated by the p38-MAPK pathway in OVCAR3 cells, Apoptosis, 10: 1383-1393, 2005.

Planey, S.L., Abrams, M., Robertson, N.M. and Litwack, G., Role of apical caspases and glucocorticoid receptor-regulated genes in glucocorticoid-induced apoptosis of pre-B leukemic cells, Cancer Research, 63: 172-178, 2003.

Planey, S.L., Derfoul, A., Steplewski, A., Robertson, N.M. and Litwack, G., Inhibition of glucocorticoid-induced apoptosis in 697 pre-B lymphocytes by the mineralocorticoid receptor N-terminal domain, J. Biol. Chem., 277: 42188-42196, 2002.

Kang, J.J., Srinivasula, S.M., Alnemri, E.S., Litwack, G., Hall, D.J. and Bjornsti, M.A., Cascades of mammalian caspase activation in the yeast Saccharomyces cerevesiae, J. Biol. Chem., 274: 3189-3198, 1999.

Walter, B.N., Huang, Z., Jakobi, R., Tuazon, P.T., Alnermri, E.S., Litwack, G. and Traugh, J.A., Cleavage and activation of P21-activated protein kinase gamma-PAK by CPP32 (caspase3); Effects of autophosphorylation on activity, J. Biol. Chem., 273: 28733-28739, 1998.

Derfoul, A., Robertson, N.M., Lingrel, J.L., Hall, D.J. and Litwack, G., Regulation of the human Na/K ATPase human β1 gene promoter by mineralocorticoid and glucocorticoid receptors, J. Biol. Chem., 273: 20702-20711, 1998.

Srinivasula, S.M., Ahmad, M., Ottilie, S., Bullrich, F., Banks, S., Wang, Y., Fernandes-Alnemri, T., Croce, C.M., Litwack, G., Tomaselli, K.J., Armstrong, R.C. and Alnemri, E.S., FLAME-1, a novel FADD-like antiapoptotic molecule that regulates FAS/TNFR-1induced apoptosis, J. Biol. Chem., 272: 18542-18545, 1997.

Sullivan, W., Stensgard, B., Caucutt, G., Bartha, B., McMahon, N., Alnemri, E.S., Litwack, G. and Toft, D., Nucleotides and two functional states of HSP90, J. Biol. Chem., 272: 8007-8012, 1997.

Bullrich, F., Fernandes-Alnemri, T., Litwack, G., Alnemri, E.S. and Croce, C.M., Chromosomal mapping of potential cell death proteases CPP32, Mch2 and Mch3, Genomics, 36: 362-365, 1996.


Takahaski, A., Alnemri, E.S., Lazebnik, Y.A., Fernandes-Alnemri, T., Litwack, G., Mori, R.D., Goldman, R.D., Poirier, G.G., Kaufman, S.H. and Earnshaw, W.C., Cleavage of lamin A by Mch2α but not CPP32: Multiple ICE-related proteases with distinct substrate recognition properties are active during apoptosis, Proc. Nat. Acad. Sci., 93: 8395-8400, 1995.

Alnemri, E.S., Fernandes-Alnemri, T. and Litwack, G., Cloning and expression of four novel isoforms of human interleukin-1β converting enzyme with different apoptotic activities, J. Biol. Chem., 270: 4312-4317, 1995.

Alnemri, E.S., Fernandes-Alnemri, T., Robertson, N.M., Pomerenke, K., Dudley, K., DuBois, G.C. and Litwack, G., FKBP46, a novel Sf9 insect cell nuclear immunophilin that forms a protein kinase complex, J. Biol. Chem., 268: 30828-30834, 1994.

Alnemri, E.S., Alnemri, T.F., Nelki, D.S., Dudley, K., DuBois, G. and Litwack, G., Overexpression, characterization and purification of a recombinant mouse immunophilin FKBP-52 and identification of an associated phosphoprotien, Proc. Nat. Acad. Sci., 90: 6839-6843, 1993.

Alnemri, E.S., Robertson, N.M., Fernandes, T.F., Croce, C.M., and Litwack, G., Overexpressed full length human BCL-2 extends the survival of baculovirus-infected Sf9 insect cells, Proc. Nat. Acad. Sci., 89: 7295-7299, 1992.

Alnemri, E.S., Maksymowych, A.B., Robertson, N.M. and Litwack, G., Overexpression and characterization of the human mineralocorticoid receptor, J. Biol. Chem., 266: 18072-18081, 1991.

Hsu, T.C., Bodine, P.V. and Litwack, G., Endogeneous modulators of glucocorticoid receptor function also regulate purified protein kinase C, J. Biol. Chem., 266: 1753-1759, 1991.

Alnemri, E.S., Maksymowych, A.B., Robertson, N.M. and Litwack, G., Characterization and purification of a functional rat glucocorticoid receptor overexpressed in a baculovirus system, J. Biol. Chem., 266: 3925-3936, 1991.

Daniel, V., Maksymowych, A., Alnemri, E.S. and Litwack, G., Cell-free synthesis of rat glucocorticoid receptor in rabbit reticulocyte lysate. In vitro synthesis of receptor in HSP-90 depleted lysate, J. Biol. Chem., 266: 1320-1325, 1991.

Alnemri, E.S. and Litwack, G., Glucocorticoid induced lymphocytolysis is not mediated by an induced nuclease, J. Biol. Chem., 264: 4104-4111, 1989.

Bodine, P.V. and Litwack, G., Purification and structural analysis of the modulator of the glucocorticoid receptor complex. Evidence that the modulator is a novel phospholipid, J. Biol. Chem., 263: 3501-3512, 1988.

Schmidt, T.J., Miller-Diener, A., Webb, M.L. and Litwack, G., Thermal activation of the purified rat hepatic glucocorticoid receptor. Evidence for a two-step mechanism, J. Biol. Chem., 260: 16255-16262, 1985.

Schmidt, T.J., Miller-Diener, A. and Litwack, G., β-Lapachone, a specific competitive inhibitor of ligand binding to the glucocorticoid receptor, J. Biol. Chem., 259: 9536-9543, 1984.

Bastl, C.P., Barnett, C.A., Schmidt, T.J. and Litwack, G., Glucocorticoid stimulation of sodium absorption in colon epithelia is mediated by corticosteroid IB receptor, J. Biol. Chem., 259: 1186-1195, 1984.

Grandics, P., Miller, A., Schmidt, T.J., Mittman, D. and Litwack, G., Purification of the unactivated glucocorticoid receptor and its subsequent in vitro activation, J. Biol. Chem., 259: 3173-3180, 1984.

DiSorbo, D.M., Phelps, D., Ohl, V.S. and Litwack, G., Pyridoxine deficiency influences the behavior of the glucocorticoid receptor complex, J. Biol. Chem., 255: 3866-3870, 1980.

Cake, M.H., DiSorbo, D.M. and Litwack, G., Effect of pyridoxal phosphate on the DNA binding site of the activated hepatic glucocorticoid receptor, J. Biol. Chem., 253: 4886-4891, 1978.

Daniel, V., Smith, G.J. and Litwack, G., Translation in vitro of rat liver messenger RNA coding for ligandin (glutathione S-transferase B), Proc. Natl. Acad. Sci., 74: 1899-1902, 1977.

Croce, C.M., Litwack, G. and Koprowski, H., Human regulatory gene for inducible tyrosine aminotransferase in rat-human hybrids, Proc. Natl. Acad. Sci., 70: 1268-1272, 1973.

Miller, J.E. and Litwack, G., Purification, properties and identity of mitochondrial tyrosine aminotransferase, J. Biol. Chem., 246: 3234, 1971.

 

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